I directed and participated actively until 2008 in the research programs of two laboratories: The Center for Morphometric Imaging and a laboratory focused upon the cell and molecular biology of early neocortical histogenesis. The former was based upon a laboratory developed, high resolution computer assisted routine providing precise quantitative analyses of the the parcellated human brain from volumetric imaging sequences. It was not limited its application by topological abnormalities that might be encountered in developmental disorders or even grossly in stroke. The second program was based upon the mouse as experimental animal where a concerted approach figuring molecular genetics, multiple histological methods and molecular biology was focused upon gradient mechanisms regulating the production in and migration from the periventricular generative epithelium. Since that time I have concentrated exclusively on clinical neurology and teaching where my activities have increasingly gravitated to a preoccupation with disorders of the autonomic nervous system where disorders of underlying small fiber neuropathy, typically remerging in the wake of infections and seemingly driven by autoimmune mechanisms are prominent.
Kennedy D, Lange N, Makris N, Bates J, Caviness VSJr (1998) Gyri of the human neocortex: an MRI-based analysis of volumes and variance. Cerebral Cort 8:372-385.
Takahashi T, Goto T, Miyama S, Nowakowski R, Caviness VSJr (1999) Sequence of neuron origin and neocortical laminar fate: relation to cell cycle of origin in the developing murine cerebral wall. J Neurosci 19:10357-10371.
Delalle I, Takahash T, Nowakowski R, Tsai L-H, Caviness VSJr (1999) Cyclin E - p27 Opposition and Regulation of the G1 Phase of the Cell Cycle In the Murine Neocortical PVE: A Quantitative Analysis of mRNA In Situ Hybridization. Cereb Cort 9:824-832.
Caviness VS, Jr., Nowakowski RS, Bhide PG (2009) Neocortical neurogenesis: morphogenetic gradients and beyond. Trends Neurosci 32:443-450.